Today, when he was asked if he was eating anything at home, Uncle Zhang said: “my relatives gave me some” earthly ginseng “, saying that it can activate blood circulation and remove blood stasis. I’ve been drinking it for half a month.”
Panax notoginseng is a plant of Acanthopanax family, which has the effects of removing blood stasis and stopping bleeding, promoting blood circulation and relieving pain. Although there is only one word difference between “Panax notoginseng” and “Panax notoginseng”, its efficacy is vastly different. More importantly, “Tusanqi” contains a substance called pyrrole alkaloid, which has strong liver toxicity. Taking it in a short time may cause liver damage. Like Uncle Zhang in the above-mentioned case, the liver is large and ascites, and even lead to liver cell necrosis and fibrosis. If taken for a long time, liver transplantation can only be carried out.
liver vessels are extremely rich, “pyrrolidine alkaloids” in “Panax notoginseng” can form a metabolite with alkylating effect in the liver, which can damage vascular endothelium and liver cells. Among them, the most easily damaged venules are hepatic lobular central vein and inferior lobular vein, whose lumen is narrow and widely occluded, so we also call it hepatic veno occlusive disease. Compared with the common thrombus, the obstruction was non thrombotic, and lymphangiosis and “liver crying” could be seen under CT.
Uncle Zhang in this article came to the hospital because of ascites. CT showed liver enlargement. The ascites and hepatomegaly often lasted for a long time. In severe cases, splenomegaly or even hepatic encephalopathy could be induced.
at present, the most effective way is to do liver tissue biopsy under laparoscopy. Under the microscope, we can see the stenosis or fibrosis and obstruction of hepatic venules, serious damage to the endothelium of hepatic sinuses, necrosis of hepatocytes, and fibrosis of hepatic sinuses.
secondly, medical history is very important. Many patients have a history of eating “Tusanqi”. Therefore, once you hear “Tusanqi” during consultation, you must pay attention to it.
imaging examination has certain diagnostic significance, such as liver enlargement or “map” and “speckle” shape changes under CT, including ascites and other symptoms, can be suspected of hepatic venule syndrome.
long term intake of “Panax notoginseng” will cause irreversible liver damage, and liver transplantation can only be performed in late stage, so it is very important to stop the intake of such substances immediately=“ https://luanban.com/category/focus/ ” target=”_ blank” rel=”noopener”>Focus