NIR even Chen of Stanford University reported a design opportunity for a more energy-efficient wireless intracortical brain computer interface. This study provides an effective hardware design for clinically feasible wireless intracortical brain computer interface, and suggests that the current circuit design parameters of recording ibci can be greatly relaxed without reducing the performance. The proposed design can save an order of magnitude of power and lead to a clinically viable ibci with a higher channel number.
recently, a study by the Korean Institute of brain science used advanced deep learning technology of antagonistic generation network to analyze the data of cerebral cortex tissue of Alzheimer’s disease mouse model. It was found that amyloid beta protein increased in the early stage of the disease and altered cholesterol biosynthesis.
researchers such as Christian broberger and Stefanos stagkourakis of Karolinska college, Sweden, and other researchers have found that hypothalamic network oscillation controls the neurohormonal circuit of father behavior. The research results were published online in the Journal on August 6, 2020.
using Sprague Dawley rats and C57BL / 6 mice, the researchers found that different electrical oscillation patterns in neuroendocrine dopamine neurons were closely related to the low dopamine release, high circulating prolactin, the activation of galanin neurons in the medial preoptic area dependent on prolactin receptor, and the behavior of paternal mice. In rats, the same parameters showed opposite characteristics. Photogenetic manipulation of these rhythms significantly altered serum prolactin and paternal behavior in mice, whereas injection of prolactin into non paternal rats triggered parental care. These findings suggest that a frequency regulated brain endocrine brain circuit can be used as a control system for determining the parental strategies of species.
a clinical study of intestinal microbiome in patients with Huntington’s disease found that it is not only a brain disease, but also a physical disease. The study, led by the Turner Institute of brain and mental health at Monash University and in collaboration with the Florey Institute of neuroscience, found evidence of intestinal malnutrition in people with HD, as well as some disease-related intestinal symptoms. The findings, published in the journal, shed light on the role of the gut in Huntington’s disease and its potential as a therapeutic intervention or a target for tracking disease progression in the future.
this paper summarizes the results of data-driven research on identifying more neural subtypes of ASD at the structural and functional levels of the brain. The steps of methodology are as follows: selection of diagnostic samples, features of neuroimaging, algorithm and verification method. Although the research methods are different, there are at least 2-4 different subtypes of ASD. Their recognition improved the accuracy of symptom prediction and diagnostic tags, exceeding the group average comparison. This paper also points out the challenges and gaps of related research: 1) need to collect more extensive and in-depth samples outside the diagnostic framework, while minimizing artifacts; 2) quantitative and unbiased methods of feature selection and multimodal fusion; 3) more emphasis on the ability of algorithms to capture ASD hybrid dimensions and classification models; 4) integrating systematic reproduction and validation of different analysis units on multiple scales. Finally, the solutions to these challenges and gaps are discussed in order to have a comprehensive understanding of the mechanism behind ASD heterogeneity. This paper is published in the journal Biological Psychology.
epidemiological studies have shown that smoking is associated with low risk of Parkinson’s disease, and nicotine plays an important role in it. There are also clinical studies to prove that nicotine is expected to become an effective drug in the treatment of Parkinson’s disease. Nicotine, as an alkaloid, exists not only in tobacco, but also in the fruits of many Solanaceae plants, such as tomato, pepper, wolfberry and so on.
recently, a large-scale prospective study was conducted on the relationship between dietary nicotine intake and PD risk in non-smokers for the first time. The study concluded that eating nicotine and foods rich in nicotine, such as tomatoes and peppers, can reduce the risk of Parkinson’s disease, and the benefits of nicotine intake in this diet are particularly significant for women. As for the results that the correlation between dietary nicotine intake and the low risk of PD is not significant, this study suggests that a more comprehensive and accurate scale should be designed to evaluate the dietary nicotine intake in order to confirm whether this gender difference is universal.
studies have shown that education plays an important role in the aging of specific hippocampal sub regions in men. The study suggests an interesting, grounded idea: the earlier a man reads, the better he will be!
purol, one of the authors, said: “it seems that happiness may not be about marriage, but about mentality. If you can find happiness and satisfaction as a single person, you are likely to stick to it, whether or not you have a ring on your finger.” Focus