Melatonin, whose name is like a whitening product, has become a sleeping aid

Melatonin, the name, we will not feel strange, and even, there are many people, as long as sleep is not good, think of using melatonin. However, some people wonder why melatonin, whose name is like a whitening product, can help sleep? What’s the effect of this sharp tool? Is it suitable for everyone? What should we pay attention to? Let’s analyze it now. < / P > < p > melatonin, also known as pineal hormone, is an amine neuroendocrine hormone secreted by the pineal gland of mammals and humans, which can make a cell that produces melanin shine, so it gets its name. Melatonin can regulate the circadian rhythm of organisms. The duration of melatonin production and secretion is related to the length of night, which is mainly regulated by the light dark cycle. < / P > < p > melatonin has many physiological functions, such as regulating immune system, tumor, aging and so on. Melatonin is an endogenous synchronization factor, which can stabilize and strengthen circadian rhythm, improve immune function, eliminate free radicals, resist stress and delay aging by correcting biological clock and neuroendocrine regulation. The secretion of melatonin is mainly affected by light, which is inhibited in the daytime and increased at night. Secondly, age will also affect it. After 35 years old, the secretion of melatonin decreases significantly, with an average of 10% to 15% every 10 years. The level of melatonin in some elderly people is only 10% of the peak. Therefore, more sleep disorders occur. Thirdly, jet lag will also affect the secretion of melatonin Some people who travel long distances, such as the stewardess of international flights, will suffer from sleep disorders. < / P > < p > more and more research evidence shows that melatonin can also affect mood, which may contribute to the treatment of mood disorders. Italian and British scholars published papers in 2017. Through retrospective study and comparison, they found that melatonin has certain adjuvant treatment effect on bipolar disorder, depression, seasonal affective disorder, etc., but the mechanism of action remains to be determined. < p > < p > melatonin also plays an important role in the regulation of energy metabolism, and has effects on body weight, insulin sensitivity, glucose tolerance, etc. Melatonin will adjust energy metabolism according to the changes of daily and environmental cycles according to the influence of time and season. For example, in spring, mammals mainly focus on energy accumulation and storage, and the body stores fat; in summer, they reduce appetite; in winter, they mainly store energy, and this cycle is regulated according to the length of sunshine. During the day, melatonin can promote insulin secretion, glycogen synthesis and glycolysis, block liver gluconeogenesis, increase adipose tissue production and adiponectin production; during rest or sleep, it can increase leptin secretion. Lack of melatonin will cause metabolic disorder, increase food intake, reduce energy consumption, and cause weight gain. Supplement of melatonin will cause weight loss. Melatonin also helps to reduce diastolic blood pressure and relieve hypertension. Animal experiments also confirmed that melatonin affects the metabolism of nutrients by regulating the secretion and activity of insulin. < / P > < p > melatonin, which helps sleep, mainly aims at circadian dysrhythmic sleep disorders, such as sleep phase delay syndrome, where the time of falling asleep and awakening is delayed by 3 to 6 hours; there is also time difference syndrome, where it is difficult to fall asleep or sleep maintenance due to changing time zone. Melatonin for those who often shift or work overtime caused by sleep disorders, the effect is more obvious. In addition, the use of melatonin in patients with sleep wake rhythm disorder, especially those with neurological disorders, will also have a better effect. < / P > < p > the mechanism of action of melatonin tells us that it is not a rational choice to take melatonin casually if you can’t sleep well or can’t sleep. The use of melatonin, need to follow the body’s own melatonin secretion time, should be taken 1 to 2 hours before going to bed, usually, slow-release melatonin, the effect lasts for a long time, the effect is better. It should be noted that long-term use of exogenous melatonin will directly inhibit the synthesis and secretion of melatonin, leading to sleep disorders. Excessive use of melatonin can also lead to poor mental state, distraction, reduced responsiveness and sensitivity. Therefore, long-distance driving or mechanical operators should use melatonin with caution. Sleep disorders have many types and complex causes. If you can’t sleep well or can’t sleep, you should seek medical advice in time, make accurate diagnosis, find out the root of the disease and treat it. Even if you need to take melatonin, you should also accept professional guidance and should not take it blindly by yourself. 08/16/2020