People who get dizzy when standing up are at a higher risk of dementia, new research reveals

In life, many people may have such experience. After lying on their back or squatting for a long time, they will feel blurred and dizzy when they suddenly stand up. In fact, it’s a symptom known as orthostatic collapse, which occurs when our brain’s blood supply can’t keep up with the body’s “rhythm.”. < / P > < p > recently, researchers from the University of California and the University of Descartes in Paris published a research report, suggesting that the frequent occurrence of such symptoms should be careful, because it implies that people have a higher risk of dementia, and that compared with ordinary people, those with sharp changes in systolic blood pressure caused by changes in body position have an increased risk of dementia 40%。 < p > < p > dementia is a kind of chronic acquired progressive intelligence disorder syndrome, which is characterized by slow intelligence decline and personality changes. Systolic blood pressure (SBP) is the lateral pressure produced by the blood injected from the ventricles to the vascular wall when the heart contracts. When postural hypotension occurs, the systolic blood pressure can rapidly drop 20 mmHg. In general, dementia is closely related to high blood pressure, but the new study suggests that it is not only hypertension, but hypotension may also be an important “promoter” of dementia. There were 73.73% of the subjects with dementia (P < 31 years old) who were enrolled in this study. During the five-year baseline period, the participants' orthostatic blood pressure was repeatedly evaluated and their systolic and diastolic blood pressures were additionally measured. Over the next 12 years, the researchers assessed participants' dementia using dementia drugs and related hospital records. < / P > < p > overall, 462 people eventually developed dementia. Of the 192 participants with systolic orthostatic hypotension, 50 developed dementia, while 412 of the 1939 participants without the symptom developed dementia. In the adjusted Cox proportional hazard model, systolic postural hypotension was associated with a 37% increased risk of Alzheimer’s disease. < / P > < p > in a further analysis, participants were divided into three groups based on changes in systolic blood pressure readings from sitting to standing. In the group with the largest fluctuation in systolic blood pressure readings, 24% of participants developed dementia, while in the group with the least fluctuation, 19% had dementia. After adjusting for other factors affecting dementia risk, the group with the highest fluctuation in systolic blood pressure readings was 35% more likely to develop dementia than the lowest group. This is not the first study on postural hypotension and dementia risk. In July 2018, researchers from Johns Hopkins University published a research report involving 11709 participants with an average age of 54 years. They proposed that compared with ordinary people, people with orthostatic hypotension have a 54% higher risk of dementia and twice the risk of ischemic stroke. “People’s blood pressure should be monitored from sitting to standing, and controlling these blood pressure drops may be a promising way to prevent dementia and help people maintain their thinking and memory when they are washing for years and months,” said Laure Rouch, PhD, forensic medicine, University of California, San Francisco, lead author of the new report < / P > < p > in summary, this study shows that blood pressure readings are closely related to the development of dementia. However, the causal relationship between the two and the association between blood pressure readings and specific types of dementia need to be explored in further experiments. Focus