Terrible Harvard publishes 20-year results: people with bad teeth have a 52% increased risk of cancer

Xiao Li, 30, is a patient with periodontal disease. For Xiao Li, the most painful thing in the world is not lack of money or love, but – looking in the mirror, he found that his teeth had turned yellow and his gums began to shrink. He sucked his teeth, and a stream of blood oozed from his teeth. The stench caused by periodontal abscess spread throughout his mouth

recently, a prospective study published in the official journal of the British Society of Gastroenterology showed that people with unhealthy periodontal or tooth loss had a higher risk of some cancers! The study was conducted by researchers from T. h. Chan School of public health and the First Affiliated Hospital of Sun Yat sen University.

the researchers analyzed 98459 women from the nurse health study and 49685 men from the health professionals follow-up study. During more than 20 years of follow-up, researchers recorded 238 cases of gastric cancer and 199 cases of esophageal cancer, and found that periodontal disease may increase the risk of gastric cancer by 52% and esophageal cancer by 43%.

the study also showed that people with more than two teeth loss had a 33% and 42% increased risk of gastric and esophageal cancer compared with those without tooth loss.

in periodontal disease patients, the risk of gastric cancer was increased by 50% in patients without tooth loss. If the number of teeth dropped was more than 1, the risk of gastric cancer was higher, which could increase by 68%. In addition, in the case of esophageal cancer, the risk of esophageal cancer increased by 59% regardless of whether or not periodontal patients lost their teeth.

Why is periodontal disease associated with cancer? This may be related to the pathogenic bacteria causing periodontal disease and overexpression of microorganisms in the oral cavity.

in daily life, bad oral hygiene habits such as not brushing teeth can promote the growth of pathogens. Some of them can cause abnormal immune and epidemic prevention functions, induce the production of pro-inflammatory cytokines, interfere with normal physiological metabolism and inhibit cell apoptosis, thus increasing the risk of cancer.

domestic studies have shown that when Porphyromonas gingivalis is implanted into normal cells, it takes less than half a year for the cells to have the basic characteristics of cancer cells!

periodontal disease is a common chronic oral infectious disease, which is usually caused by oral bacteria. When your mouth appears gingival swelling, gingival bleeding, halitosis, plaque deposition and other phenomena, you should be vigilant. According to the fourth national oral health epidemiological survey in China, the detection rate of oral calculus and gingival bleeding among people aged 35-44 is 96.7% and 87.4%, respectively. The periodontal health status of the people is not optimistic!

more and more studies have shown that periodontal disease not only affects the local periodontal tissue of the oral cavity, but also is closely related to gastric cancer, oral cancer, pancreatic cancer, etc., and periodontal pathogens can also affect the whole system, inducing cardiovascular and cerebrovascular diseases, diabetes, rheumatoid arthritis, poor pregnancy, chronic kidney disease, inflammatory bowel disease and other diseases.

periodontal pathogens can promote the production of inflammatory cytokines, aggravate systemic inflammatory response, and promote the occurrence of diabetes. At the same time, periodontal pathogens can directly enter the digestive system and affect the development of diabetes by changing intestinal microbiota.

periodontal pathogens can enter the circulatory system, set values in tissues and organs and cause autoimmune response, thus promoting the occurrence of rheumatoid arthritis.

periodontal pathogens can enter the placenta of pregnant women and reach the amniotic fluid and fetal body, bringing negative effects to the fetus. Excessive intraplacental inflammatory amniotic fluid can increase uterine muscle contraction and induce premature delivery.

periodontal pathogens can promote the release of inflammatory cytokines, aggravate systemic inflammatory response, and induce kidney inflammation, which is the inducement of chronic kidney disease. Some studies have shown that moderate periodontitis is a risk factor for nephritis or even chronic renal failure!

studies have shown that the presence of “non hemolytic streptococcus” in dental lesions can cause colitis, and colitis will subside after these bacteria are removed from the lesions.

“small periodontal disease” can induce so many and serious systemic diseases, which is really unexpected! Therefore, in order to prevent the occurrence of periodontal disease, we should develop good oral hygiene habits, brush teeth at least twice a day, every time brush teeth should be taken seriously, must not be perfunctory.

we can use pasteurization to brush our teeth. Babbitt brushing is an effective method to remove dental plaque recommended by American Dental Association. How to operate it?

first of all, hold a soft toothbrush, the bristles should be at a 45 ° angle with the root of the teeth, and slightly press the toothbrush to make part of the bristles enter into the gingival sulcus and some into the gingival margin;

in addition to brushing teeth well, we should also pay attention to the daily care of teeth: gargle after meals, and learn to use dental floss to clean teeth, and do not let food residue “stay” in the mouth for too long; check regularly every year Check the teeth and wash them under the guidance of the stomatologist; pay attention to eat less spicy and sour food to avoid enamel erosion; friends who have oral symptoms such as halitosis, gingival bleeding and periodontal abscess should go to the hospital in time and receive regular treatment as soon as possible.

there are a lot of people around Xiaobian who don’t like brushing their teeth. Every time they brush their teeth, they gobble it up. In fact, they can’t clean the mouth at all, thus “conniving” the germs to “commit crimes” in the body, thus laying a foundation for future diseases. Therefore, if you want to prevent disease, you should start from brushing your teeth!

[2] LAN Zijun, Yuan Xiang, et al. Study on the role and mechanism of Porphyromonas gingivalis in digestive system tumors. Esophageal diseases [J]. March 25, 2020
[4] Du Qin. Ma Xinru. Research progress on the relationship between periodontal pathogens and systemic diseases. Journal of Southern Medical University. 2020, 40

[5] Li Zhengyang. Relationship between periodontal disease and systemic diseases. Journal of Logistics College of armed police. 2012, 21 < a href=" https://luanban.com/after-pregnancy-do-not-let-the-wife-do-these-five-kinds-of-housework-the-husband-should-be-responsible-for-it-otherwise-it-is-easy-to-hurt-the-fetus/ " target="_ blank" rel="noopener">After pregnancy, do not let the wife do these five kinds of housework, the husband should be responsible for it, otherwise it is easy to hurt the fetus!