The appearance of this “guy” often indicates that the prognosis of kidney disease is poor, and it needs to be dealt with in time in the early stage!

We can often see “Crescent” in renal biopsy reports, including cellular crescent, fibrocytic crescent and fibrous crescent. < / P > < p > < p > at first glance, the name “Crescent” seems to have little “lethality”. It can make people think of a curved moon, and it is a little poetic. But in fact, it is a “cruel role”, which is one of the important signs of poor prognosis of kidney disease. Here we will explain it. Baidu Encyclopedia explains as follows: “crescent is a crescent shaped body formed around the capillary plexus, in which epithelial cells in the wall layer of renal small balloon proliferate significantly and accumulate into layers.” In short, the crescent is a crescent shaped thing formed by the accumulation of various kinds of cells leaked from the renal blood vessels. These cells include blood cells, cellulose, infiltrating monocytes, proliferating parietal epithelial cells, etc. In the state of intact renal function, the components of crescent moon are all present in the blood. When the kidney is damaged, the glomerular vascular wall ruptures, they “slip out” and form a crescent shaped or circular structure outside the capillary bulb. < / P > < p > through renal puncture, dozens of glomeruli are taken and examined under light microscope. If there is a crescent like thing in the glomerulus, it is crescent body. The appearance of crescentic body often indicates that the pathological damage of kidney is relatively serious, which is common in severe injury and rupture of glomerular capillary wall caused by various reasons, which is an important sign of poor prognosis. The more the number of crescent, the more serious kidney damage caused by crescent. If not treated in time, it is easy to aggravate the deterioration of renal function, and even lead to the early arrival of uremia. There is a type of kidney disease called crescentic glomerulonephritis, which has a ferocious force and can rapidly develop into oliguria, anuria and renal failure with a poor prognosis. Some kidney friends may think that having crescent is getting Crescentic Nephritis. In fact, the two are not the same thing. Crescentic glomerulonephritis is a more serious situation, only when more than 50% of the glomeruli appear crescentic glomerulonephritis. < p > < p > we usually have some common kidney diseases, such as lupus nephritis, IgA nephropathy, membranous nephropathy, ANCA related vasculitis and so on. However, as long as the proportion does not reach 50%, it does not belong to Crescentic Nephritis. Don’t scare yourself. < / P > < p > as we said above, the more crescent, the more serious the kidney damage. Conversely, the less the number of crescent, the lighter the condition. At this time, timely treatment, the prognosis will be greatly improved. < / P > < p > in addition, the early crescent is mainly composed of cells, which is called cellular crescent. At this time, it is better to treat it. When the collagen fibers increase and develop into fibrocytic crescent and fibrous crescent, the treatment difficulty will increase. Therefore, the earlier the crescent is treated, the better the treatment will be. 08/16/2020